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Yasumitsu Nishimura|chemical analysis of titanate nanosheets (TNS) as 2D materials in human immune cells

Date:2017-08-03Author:
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Yasumitsu Nishimura

Ph.D

Association Professor

Department of Hygiene

Kawasaki Medical School

Japan


Dr. Yasumitsu Nishimura was a visiting fellow at Green Templeton College, Oxford University (2016-2017). His major research interest is about immunological effects of mineral particles and fibers in association with occupational health. His ongoing effort is to establish screening devices for detection of occupational cancers (e.g., mesothelioma) on the basis of immunological analyses. He also investigates physical and chemical characteristics of titanate nanosheet using various techniques (TEM, SEM, EDX, et.al) as well as adverse health effects.  Since 2005, he received 8 awards/honors in the field of occupational hygiene and medicine.


Topic of Lecture: Physical – chemical analysis of titanate nanosheets (TNS) as 2D materials in human immune cells


Abstract: Titanate nanosheets (TNS) are crystalline materials composed of titanium and oxygen with very thin and flat structure, 2D materials. TNS are expected to be valuable materials for production of UV- or corrosion-resistant films, dielectric thin films and catalysts in industry. The present study demonstrated the human peripheral blood mononuclear cells (PBMC) may uptake TNS. Indeed, the formation of giant vacuole of cells was present with nano-scaled structures like TNS determined using TEM. The SEM with energy dispersion type X-ray spectroscopy (EDX) showed rough area on the inner side of vacuolar membrane as well as the existence of titanium. These techniques and results might be helpful for monitoring adverse health effects of nanomaterial.